Catalytic α-Arylation of Imines Leading to N-Unprotected Indoles and Azaindoles
نویسندگان
چکیده
A palladium N-heterocyclic carbene catalyzed methodology for the synthesis of substituted, N-unprotected indoles and azaindoles is reported. The protocol permits access to various, highly substituted members of these classes of compounds. Although two possible reaction pathways (deprotonative and Heck-like) can be proposed, control experiments, supported by computational studies, point toward a deprotonative mechanism being operative.
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عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2016